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-   -   Annie: Diabetic with new Cushings diagnosis (http://k9diabetes.com/forum/showthread.php?t=7878)

katy1 04-29-2019 08:42 PM

Re: Annie: Diabetic with new Cushings diagnosis
 
I have to admit, that I do not test at home. I have to rely on my vet tech for that. I’m not sure how long he will keep her on the current amount, but the weight she is at, Royal Canin recommends 1 2/3 can so we just rounded it up.

Raysaint 05-02-2019 06:41 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
I think most believe that home testing is so important. It lets you have more control over the management. And it saves you trips and money.

katy1 05-08-2019 08:11 PM

Re: Annie: Diabetic with new Cushings diagnosis
 
Annie had a bg curve today and as a result, doc raised her insulin from 7 to 8 units 2x a day. They will do another curve next Thursday.

If anyone is interested, I ‘ll be happy to post numbers. Doc said the curve looked good but it was too high. Blessings to you all. Karen

jesse girl 05-09-2019 07:11 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
Yes you can post the curve and we can have a look see

katy1 05-09-2019 09:56 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
Annie's curve based on 7 units of insulin. Doc has bumped it up to 8.

8:50.............438

9:46.............344

10:49...........259

11:48...........213

12.51...........232

1:57............229

3:00............267

4:00............290


Thanks for any input. Karen

jesse girl 05-09-2019 10:13 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
one unit is reasonable

MikeMurphy 05-09-2019 12:36 PM

Re: Annie: Diabetic with new Cushings diagnosis
 
Nice curve! She’s making good progress:)

katy1 05-11-2019 11:01 PM

Re: Annie: Diabetic with new Cushings diagnosis
 
I have a question. Does Lysodren have any effect on insulin in a dual diagnosis pup? Annie is currently on 250mg of Lysodren 2x per week and was just bumped up to 8 units of insulin 2x a day after meals, but her food intake has doubled also........just curious if there is any connection between the Lysodren and insulin.

It’s so frustrating sometimes to have to come here to get info for her diabetes and then have to source the k9C site for her cushings. I feel like I’m the only person in the world with a dual diagnosis pup. I apologize for th little rant.

I’m truly grateful my little baby is still alive and thriving after everything she has been through over the past month. I’m talking about a 10 year old miniature schnauzer, diabetic, pancreatitis, gallbladder removal surgery and the list goes on.

Blessings to you all.

labblab 05-12-2019 07:05 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
Hi Karen! It’ll be great for the folks here to also add their insight. But from what I understand about dual diagnosis dogs, I believe this is the relationship. Excessively high cortisol levels in the body can fuel elevations in glucose levels, as well. When cortisol levels are high and uncontrolled, it can be difficult to effectively reduce glucose levels, even when giving increasingly higher doses of insulin. Insulin resistance of this type can be one of the diagnostic indicators that a diabetic dog may be suffering from Cushing’s, as well.

Once the elevated cortisol of Cushing’s comes under therapeutic control, then the glucose level and insulin requirement will likely be reduced, too. Any medication that lowers cortisol — be it Lysodren or trilostane — will have this effect. So it’s an inverse relationship: As Lysodren or trilostane doses are increased, insulin needs may be reduced.

In Annie’s case, her maintenance Lysodren dose has remained unchanged since March. Per her recent ACTH test, her cortisol level has increased a bit during this time, but not enough that I would think it would noticeably affect her glucose level or insulin needs. But this is one of the reasons why I think it would be good to have her cortisol level rechecked in about a month. There are so many interlocking pieces to the dual diagnosis puzzle that it’s important to monitor lab results on a regular basis so that medication doses can be altered in a timely fashion. If her cortisol level continues to rise on the unchanged Lysodren dose, that could account for ever higher glucose readings, too, and the need for more insulin.

Marianne

jesse girl 05-12-2019 07:45 AM

Re: Annie: Diabetic with new Cushings diagnosis
 
As Marianne suggested There is a symbiotic relationship between the 2 diseases

You are seeing a good response from insulin without a high dose that may point to cortisol levels in an adequate range

Actually its quite amazing the response you are seeing from insulin and hope that continues but expect ups and downs thats the nature of the disease


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