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Using Humulin R with Humulin N

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  • Using Humulin R with Humulin N

    This will be long!

    In Nov 2011 I got up around 6pm, after nursing Lily (at the time 6 months old), to find my Yorkie/Silky limp on the bathroom floor. My husband was in the middle of the Indian Ocean and I was alone!

    I picked her up, grabbed the baby and put both in the car and then got our other dog and took her as well to the vet. Mandy (the diabetic) was tested and found to have a BG of 790 and was in diabetic ketoacidosis. I was told they closed in an hour I had to take her to the ER vet. At 2am, still waiting to be seen, I broke down and was no longer weeping but full blown wailing out crys for help.

    She spent the weekend there and then I took her to the vet.

    She was put on Humalin NPH 5u 2 times a day. It has been 6 months and she is still uncontrolled...until a few days ago.

    I had asked my vet for other options other than Humalin N and was told I could put her in a 24 insulin. I told him that is the problem...she doesnt eat when you want her to eat and doesnt always eat the same amount and even worse she never ate dog food before all this happened. We were now mixing diabetic dog food with water in a mixer and syringe feeding her and she went from 15 lbs to 11! She wasnt overweight to begin with and now she is starving! (BTW she was on long term steriods for a skin allergy which caused the diabetes).

    I said that the problem is she needs a fast acting short duration insulin to give her when she does eat.

    He said that is not possible. I found this hard to believe seeing how insulin trials have to be tested on animals! He said no way to the Humalin R (fast and short).

    So i did a bit of reseach and found that I could get it and I did.

    I AM NOT A VET AND NOT A DOCTOR - just presenting this information as a possible solution for some dogs.

    I found out what the correct dosing was per unit of Humulin R per kilo of weight per day. I started out at the lowest 0.5 of HR and the ususal NPH 5.5u.

    We now have several hours during the day where her BG (we tested every hour for 2 weeks while trying out this new insulin) is mostly under 300 and gets to 200 for many hours of the day. before she was always 300-700 evenwith upping her HN by 0.5u she would crash and have seizures. So now we are giving her the HR at 0.5u at times that she eats.

  • #2
    Re: Using Humulin R with Humulin N

    We are one of a few people who used Regular insulin only with our dog. But it's also great for dogs who get a big spike in blood sugar after eating. It would be great if vets generally got more familiar with how to use it and what kinds of curves it works for.

    Natalie

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    • #3
      Re: Using Humulin R with Humulin N

      it kept jesse in relativity good blood sugar till we could find a routine that worked for her we use it just for corrective measures now most times its not needed it can be a very good tool in the battle
      Jesse-26 lbs - 16.5 years old ,11 years diabetic, one meal a day homemade and a vitabone snack . 3 shots of Novolin( under the Relion name ) a day . Total insulin for a 24 hour period is 6.5 units of NPH insulin .
      Jesse earned her wings on 6/21/2021

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      • #4
        Re: Using Humulin R with Humulin N

        I tried Regular 'R' at one point with Mildred (along with Humulin N) but found it had too long of a duration which caused some insulin overlap.

        I switched to Humalog (along with Humulin N) which had a duration of about 5 hours, in and out so did not see the overlap.

        I used Humalog for a few years, it was a lifesaver for Mildred.

        Eileen and Mildred, 12 yo Border Collie Mx, 24.6 pounds, dx diabetic/hypothyroid 2004, gallbladder removed 2005, cataract surgery 2005, spindle cell sarcoma removed 2009, stroke 2009, tail removed 2011, dx with bladder cancer 2011, CDS, Organix~chicken / NPH,Humalog

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